Genomics England

TNNI3

troponin I3, cardiac type

OMIM: 191044

Panel	Mode of inheritance	Details
Filter panels3 panels
Green in Dilated and arrhythmogenic cardiomyopathy Component of the following Super Panels: - Sudden unexplained death or survivors of a cardiac event - Unexplained death in infancy and sudden unexplained death in childhood R-numbers: R132 Signed-off version 2.32	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Phenotypes Cardiomyopathy, dilated, 1FF (613286), Cardiomyopathy, dilated, 2A,, ?Cardiomyopathy, dilated, 2A (611880), Cardiomyopathy, familial restrictive, 1 (115210), Cardiomyopathy, dilated, 1FF, Cardiomyopathy, hypertrophic, 7 (613690)
Green in Hypertrophic cardiomyopathy Component of the following Super Panels: - Sudden unexplained death or survivors of a cardiac event - Unexplained death in infancy and sudden unexplained death in childhood R-numbers: R131 Signed-off version 4.16	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Phenotypes Cardiomyopathy, familial hypertrophic, 7, ?Cardiomyopathy, dilated, 2A (611880), Cardiomyopathy, dilated, 1FF (613286), Cardiomyopathy, familial restrictive, 1 (115210), Cardiomyopathy, hypertrophic, 7 (613690)
Green in Paediatric or syndromic cardiomyopathy Component of the following Super Panels: - Unexplained death in infancy and sudden unexplained death in childhood R-numbers: R135 Signed-off version 5.13	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Phenotypes Hypertrophic cardiomyopathy, Cardiomyopathy, familial hypertrophic, 7, Cardiomyopathy, dilated, 1FF, Cardiomyopathy, dilated, 2A,