Genomics England
GMS Panels
Panels
Genes and Entities

NEXN

nexilin F-actin binding protein
OMIM: 613121
PanelMode of inheritanceDetails
2 panels
Green
in Dilated and arrhythmogenic cardiomyopathy
Component of the following Super Panels:
  • - Sudden unexplained death or survivors of a cardiac event
  • - Unexplained death in infancy and sudden unexplained death in childhood
R-numbers: R132
Signed-off version 2.32
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Cardiomyopathy, dilated, 1CC, OMIM:613122
Green
in Paediatric or syndromic cardiomyopathy
Component of the following Super Panels:
  • - Unexplained death in infancy and sudden unexplained death in childhood
R-numbers: R135
Signed-off version 5.13
BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Phenotypes
Cardiomyopathy, dilated, 1CC, OMIM:613122, Cardiomyopathy, hypertrophic, 20, OMIM:613876