Genomics England
GMS Panels
Panels
Genes and Entities

KRT10

keratin 10
OMIM: 148080
PanelMode of inheritanceDetails
5 panels
Green
in Epidermolysis bullosa and congenital skin fragility
R-numbers: R164
Signed-off version 2.2
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Epidermolytic hyperkeratosis, OMIM:113800
Green
in Ichthyosis and erythrokeratoderma
R-numbers: R165
Signed-off version 3.2
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Epidermolytic hyperkeratosis (EHK), OMIM:113800, ichthyosis with confetti, OMIM:609165, Ichthyosis, cyclic, with epidermolytic hyperkeratosis, OMIM:607602
Green
in Mosaic skin disorders - deep sequencing
R-numbers: R327
Signed-off version 2.0
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Epidermolytic hyperkeratosis, Palmoplantar keratoderma, Ichythosis with confetti, Pachyonychia congenita
Green
in Palmoplantar keratodermas
R-numbers: R166
Signed-off version 3.0
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Pachyonychia congenita, Palmoplantar keratoderma, Ichythosis with confetti, Epidermolytic hyperkeratosis
Green
in Pigmentary skin disorders
R-numbers: R236
Signed-off version 3.0
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Phenotypes
CRIE, Ichythosis with confetti, Pachyonychia congenita, Palmoplantar keratoderma, Epidermolytic hyperkeratosis, ERYTHRODERMA, ICHTHYOSIFORM, CONGENITAL RETICULAR