Genomics England
GMS Panels
Panels
Genes and Entities

FGA

fibrinogen alpha chain
OMIM: 134820
PanelMode of inheritanceDetails
3 panels
Green
in Bleeding and platelet disorders
R-numbers: R90
Signed-off version 3.0
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Phenotypes
202400 Afibrinogenemia, congenital, 616004 Hypodysfibrinogenemia, congenital, 105200 Amyloidosis, familial visceral, 616004 Dysfibrinogenemia, congenital
Green
in Hereditary systemic amyloidosis
Component of the following Super Panels:
  • - Unexplained young onset end-stage renal disease
R-numbers: R204
Signed-off version 1.22
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Amyloidosis, familial visceral, OMIM:105200
Green
in Thrombophilia with a likely monogenic cause
R-numbers: R97
Signed-off version 2.2
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Phenotypes
202400 Afibrinogenemia, congenital, 105200 Amyloidosis, familial visceral, 616004 Dysfibrinogenemia, congenital, 616004 Hypodysfibrinogenemia, congenital